Most Recent Publications

Year Title Link
2021 Interleukin 22 mitigates endothelial glycocalyx shedding after lipopolysaccharide injury
2020 Interleukin-22 drives a metabolic adaptive reprogramming to maintain mitochondrial fitness and treat liver injury
2020 Interleukin-22 inhibits respiratory syncytial virus production by blocking virus-mediated subversion of cellular autophagy
2020 IL-22 receptor signaling in paneth cells is critical for their maturation, microbiota colonization, Th17-related immune responses, and anti-salmonella immunity
2020 Interleukin-22 ameliorates neutrophil-driven nonalcoholic steatohepatitis through multiple targets
2020 Interleukin-22 ameliorates acute-on-chronic liver failure by reprogramming impaired regeneration pathways in mice
2019 An open-label, dose-escalation study to assess the safety and efficacy of IL-22 agonist F-652 in patients with alcohol-associated hepatitis
2019 Targeting the IL-22/IL-22BP axis enhances tight junctions and reduces inflammation during influenza infection
2018 Safety, pharmacokinetics, and biomarkers of F-652, a recombinant human interleukin-22 dimer, in healthy subjects
2018 Liver-heart crosstalk controls IL-22 activity in cardiac protection after myocardial infarction
2018 Enhanced regeneration and hepatoprotective effects of interleukin 22 fusion protein on a predamaged liver undergoing partial hepatectomy
2016 Critical role of IL-22/IL22-RA1 signaling in pneumococcal pneumonia
2015 Interleukin-22 promotes intestinal-stem-cell-mediated epithelial regeneration
2015 Biologically active, high levels of interleukin-22 inhibit hepatic gluconeogenesis but do not affect obesity and its metabolic consequences