Publications

Most Recent Publications

Year Title Link
2021 Interleukin 22 mitigates endothelial glycocalyx shedding after lipopolysaccharide injury https://pubmed.ncbi.nlm.nih.gov/33502147/
2020 Interleukin-22 drives a metabolic adaptive reprogramming to maintain mitochondrial fitness and treat liver injury https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7254999/
2020 Interleukin-22 inhibits respiratory syncytial virus production by blocking virus-mediated subversion of cellular autophagy https://pubmed.ncbi.nlm.nih.gov/32580124/
2020 IL-22 receptor signaling in paneth cells is critical for their maturation, microbiota colonization, Th17-related immune responses, and anti-salmonella immunity https://pubmed.ncbi.nlm.nih.gov/33060802/
2020 Interleukin-22 ameliorates neutrophil-driven nonalcoholic steatohepatitis through multiple targets https://pubmed.ncbi.nlm.nih.gov/31705800/
2020 Interleukin-22 ameliorates acute-on-chronic liver failure by reprogramming impaired regeneration pathways in mice https://pubmed.ncbi.nlm.nih.gov/31786256/
2019 An open-label, dose-escalation study to assess the safety and efficacy of IL-22 agonist F-652 in patients with alcohol-associated hepatitis https://pubmed.ncbi.nlm.nih.gov/31774566/
2019 Targeting the IL-22/IL-22BP axis enhances tight junctions and reduces inflammation during influenza infection https://pubmed.ncbi.nlm.nih.gov/31597930/
2018 Safety, pharmacokinetics, and biomarkers of F-652, a recombinant human interleukin-22 dimer, in healthy subjects https://pubmed.ncbi.nlm.nih.gov/29670279/
2018 Liver-heart crosstalk controls IL-22 activity in cardiac protection after myocardial infarction https://pubmed.ncbi.nlm.nih.gov/30214638/
2018 Enhanced regeneration and hepatoprotective effects of interleukin 22 fusion protein on a predamaged liver undergoing partial hepatectomy https://pubmed.ncbi.nlm.nih.gov/30515423/
2016 Critical role of IL-22/IL22-RA1 signaling in pneumococcal pneumonia https://pubmed.ncbi.nlm.nih.gov/27456484/
2015 Interleukin-22 promotes intestinal-stem-cell-mediated epithelial regeneration https://pubmed.ncbi.nlm.nih.gov/26649819/
2015 Biologically active, high levels of interleukin-22 inhibit hepatic gluconeogenesis but do not affect obesity and its metabolic consequences https://pubmed.ncbi.nlm.nih.gov/26064446/